diff --git a/Modules/FindPython/Support.cmake b/Modules/FindPython/Support.cmake
index 0f9d568454..1386117c9f 100644
--- a/Modules/FindPython/Support.cmake
+++ b/Modules/FindPython/Support.cmake
@@ -904,7 +904,7 @@ function (_PYTHON_VALIDATE_INTERPRETER)
     # interpreter does not exist anymore
     set_property (CACHE _${_PYTHON_PREFIX}_Interpreter_REASON_FAILURE PROPERTY VALUE "Cannot find the interpreter \"${_${_PYTHON_PREFIX}_EXECUTABLE}\"")
     set_property (CACHE _${_PYTHON_PREFIX}_EXECUTABLE PROPERTY VALUE "${_PYTHON_PREFIX}_EXECUTABLE-NOTFOUND")
-    if (WIN32)
+    if (WIN32 AND DEFINED CACHE{_${_PYTHON_PREFIX}_EXECUTABLE_DEBUG})
       set_property (CACHE _${_PYTHON_PREFIX}_EXECUTABLE_DEBUG PROPERTY VALUE "${_PYTHON_PREFIX}_EXECUTABLE_DEBUG-NOTFOUND")
     endif()
     return()
@@ -935,7 +935,7 @@ function (_PYTHON_VALIDATE_INTERPRETER)
       # interpreter is not usable
       set_property (CACHE _${_PYTHON_PREFIX}_Interpreter_REASON_FAILURE PROPERTY VALUE "Cannot use the interpreter \"${_${_PYTHON_PREFIX}_EXECUTABLE}\"")
       set_property (CACHE _${_PYTHON_PREFIX}_EXECUTABLE PROPERTY VALUE "${_PYTHON_PREFIX}_EXECUTABLE-NOTFOUND")
-      if (WIN32)
+      if (WIN32 AND DEFINED CACHE{_${_PYTHON_PREFIX}_EXECUTABLE_DEBUG})
         set_property (CACHE _${_PYTHON_PREFIX}_EXECUTABLE_DEBUG PROPERTY VALUE "${_PYTHON_PREFIX}_EXECUTABLE_DEBUG-NOTFOUND")
       endif()
       return()
@@ -963,6 +963,9 @@ function (_PYTHON_VALIDATE_INTERPRETER)
         # interpreter has wrong version
         set_property (CACHE _${_PYTHON_PREFIX}_Interpreter_REASON_FAILURE PROPERTY VALUE "Wrong version for the interpreter \"${_${_PYTHON_PREFIX}_EXECUTABLE}\"")
         set_property (CACHE _${_PYTHON_PREFIX}_EXECUTABLE PROPERTY VALUE "${_PYTHON_PREFIX}_EXECUTABLE-NOTFOUND")
+        if (WIN32 AND DEFINED CACHE{_${_PYTHON_PREFIX}_EXECUTABLE_DEBUG})
+          set_property (CACHE _${_PYTHON_PREFIX}_EXECUTABLE_DEBUG PROPERTY VALUE "${_PYTHON_PREFIX}_EXECUTABLE_DEBUG-NOTFOUND")
+        endif()
         return()
       else()
         # check that version is OK
@@ -972,6 +975,9 @@ function (_PYTHON_VALIDATE_INTERPRETER)
             OR NOT version VERSION_GREATER_EQUAL _PVI_VERSION)
           set_property (CACHE _${_PYTHON_PREFIX}_Interpreter_REASON_FAILURE PROPERTY VALUE "Wrong version for the interpreter \"${_${_PYTHON_PREFIX}_EXECUTABLE}\"")
           set_property (CACHE _${_PYTHON_PREFIX}_EXECUTABLE PROPERTY VALUE "${_PYTHON_PREFIX}_EXECUTABLE-NOTFOUND")
+          if (WIN32 AND DEFINED CACHE{_${_PYTHON_PREFIX}_EXECUTABLE_DEBUG})
+            set_property (CACHE _${_PYTHON_PREFIX}_EXECUTABLE_DEBUG PROPERTY VALUE "${_PYTHON_PREFIX}_EXECUTABLE_DEBUG-NOTFOUND")
+          endif()
           return()
         endif()
       endif()
@@ -984,6 +990,9 @@ function (_PYTHON_VALIDATE_INTERPRETER)
         # interpreter has invalid version
         set_property (CACHE _${_PYTHON_PREFIX}_Interpreter_REASON_FAILURE PROPERTY VALUE "Wrong version for the interpreter \"${_${_PYTHON_PREFIX}_EXECUTABLE}\"")
         set_property (CACHE _${_PYTHON_PREFIX}_EXECUTABLE PROPERTY VALUE "${_PYTHON_PREFIX}_EXECUTABLE-NOTFOUND")
+        if (WIN32 AND DEFINED CACHE{_${_PYTHON_PREFIX}_EXECUTABLE_DEBUG})
+          set_property (CACHE _${_PYTHON_PREFIX}_EXECUTABLE_DEBUG PROPERTY VALUE "${_PYTHON_PREFIX}_EXECUTABLE_DEBUG-NOTFOUND")
+        endif()
         return()
       endif()
     endif()
@@ -1006,6 +1015,9 @@ function (_PYTHON_VALIDATE_INTERPRETER)
           set_property (CACHE _${_PYTHON_PREFIX}_Interpreter_REASON_FAILURE PROPERTY VALUE "Wrong major version for the interpreter \"${_${_PYTHON_PREFIX}_EXECUTABLE}\"")
         endif()
         set_property (CACHE _${_PYTHON_PREFIX}_EXECUTABLE PROPERTY VALUE "${_PYTHON_PREFIX}_EXECUTABLE-NOTFOUND")
+        if (WIN32 AND DEFINED CACHE{_${_PYTHON_PREFIX}_EXECUTABLE_DEBUG})
+          set_property (CACHE _${_PYTHON_PREFIX}_EXECUTABLE_DEBUG PROPERTY VALUE "${_PYTHON_PREFIX}_EXECUTABLE_DEBUG-NOTFOUND")
+        endif()
         return()
       endif()
     endif()
@@ -1030,6 +1042,9 @@ function (_PYTHON_VALIDATE_INTERPRETER)
         set_property (CACHE _${_PYTHON_PREFIX}_Interpreter_REASON_FAILURE PROPERTY VALUE "Wrong architecture for the interpreter \"${_${_PYTHON_PREFIX}_EXECUTABLE}\"")
       endif()
       set_property (CACHE _${_PYTHON_PREFIX}_EXECUTABLE PROPERTY VALUE "${_PYTHON_PREFIX}_EXECUTABLE-NOTFOUND")
+      if (WIN32 AND DEFINED CACHE{_${_PYTHON_PREFIX}_EXECUTABLE_DEBUG})
+        set_property (CACHE _${_PYTHON_PREFIX}_EXECUTABLE_DEBUG PROPERTY VALUE "${_PYTHON_PREFIX}_EXECUTABLE_DEBUG-NOTFOUND")
+      endif()
       return()
     endif()
 
@@ -1056,6 +1071,9 @@ function (_PYTHON_VALIDATE_INTERPRETER)
           set_property (CACHE _${_PYTHON_PREFIX}_Interpreter_REASON_FAILURE PROPERTY VALUE "Wrong architecture for the interpreter \"${_${_PYTHON_PREFIX}_EXECUTABLE}\"")
         endif()
         set_property (CACHE _${_PYTHON_PREFIX}_EXECUTABLE PROPERTY VALUE "${_PYTHON_PREFIX}_EXECUTABLE-NOTFOUND")
+        if (WIN32 AND DEFINED CACHE{_${_PYTHON_PREFIX}_EXECUTABLE_DEBUG})
+          set_property (CACHE _${_PYTHON_PREFIX}_EXECUTABLE_DEBUG PROPERTY VALUE "${_PYTHON_PREFIX}_EXECUTABLE_DEBUG-NOTFOUND")
+        endif()
         return()
       endif()
     endif()