diff --git a/Modules/Compiler/GNU.cmake b/Modules/Compiler/GNU.cmake
index 764fbf990f..d1ca85e3dd 100644
--- a/Modules/Compiler/GNU.cmake
+++ b/Modules/Compiler/GNU.cmake
@@ -52,7 +52,7 @@ macro(__compiler_gnu lang)
   set(CMAKE_${lang}_FLAGS_RELWITHDEBINFO_INIT "-O2 -g -DNDEBUG")
   set(CMAKE_${lang}_CREATE_PREPROCESSED_SOURCE "<CMAKE_${lang}_COMPILER> <DEFINES> <INCLUDES> <FLAGS> -E <SOURCE> > <PREPROCESSED_SOURCE>")
   set(CMAKE_${lang}_CREATE_ASSEMBLY_SOURCE "<CMAKE_${lang}_COMPILER> <DEFINES> <INCLUDES> <FLAGS> -S <SOURCE> -o <ASSEMBLY_SOURCE>")
-  if(NOT APPLE)
+  if(NOT APPLE OR NOT CMAKE_${lang}_COMPILER_VERSION VERSION_LESS 4) # work around #4462
     set(CMAKE_INCLUDE_SYSTEM_FLAG_${lang} "-isystem ")
   endif()
 endmacro()