diff --git a/Modules/CMakeDetermineCompilerABI.cmake b/Modules/CMakeDetermineCompilerABI.cmake
index 53eaf58c0b..acd372eed6 100644
--- a/Modules/CMakeDetermineCompilerABI.cmake
+++ b/Modules/CMakeDetermineCompilerABI.cmake
@@ -256,6 +256,11 @@ function(CMAKE_DETERMINE_COMPILER_ABI lang src)
         endif()
       endif()
 
+      # Filter out implicit link directories excluded by our Platform/<os>* modules.
+      if(DEFINED CMAKE_PLATFORM_IMPLICIT_LINK_DIRECTORIES_EXCLUDE)
+        list(REMOVE_ITEM implicit_dirs ${CMAKE_PLATFORM_IMPLICIT_LINK_DIRECTORIES_EXCLUDE})
+      endif()
+
       # Filter out implicit link directories excluded by the environment.
       if(DEFINED ENV{CMAKE_${lang}_IMPLICIT_LINK_DIRECTORIES_EXCLUDE})
         list(REMOVE_ITEM implicit_dirs $ENV{CMAKE_${lang}_IMPLICIT_LINK_DIRECTORIES_EXCLUDE})
diff --git a/Modules/Platform/Darwin-Initialize.cmake b/Modules/Platform/Darwin-Initialize.cmake
index 1a47d9abd8..245170c390 100644
--- a/Modules/Platform/Darwin-Initialize.cmake
+++ b/Modules/Platform/Darwin-Initialize.cmake
@@ -292,4 +292,11 @@ if(NOT CMAKE_OSX_SYSROOT)
     RESULT_VARIABLE _result
   )
   unset(_sdk_macosx)
+
+  list(APPEND CMAKE_PLATFORM_IMPLICIT_LINK_DIRECTORIES_EXCLUDE
+    # Without -isysroot, some compiler drivers implicitly pass -L/usr/local/lib
+    # to the linker.  Since the macOS dynamic loader does not search it by
+    # default, it is not a fully-implemented implicit link directory.
+    /usr/local/lib
+  )
 endif()