diff --git a/libs/python/agent/agent/loops/uiins.py b/libs/python/agent/agent/loops/uiins.py
new file mode 100644
index 00000000..b7b4a5c7
--- /dev/null
+++ b/libs/python/agent/agent/loops/uiins.py
@@ -0,0 +1,177 @@
+"""
+UI-Ins agent loop implementation for click prediction using litellm.acompletion
+Paper: https://arxiv.org/pdf/2510.202861
+Code: https://github.com/alibaba/UI-Ins
+"""
+
+import asyncio
+import base64
+import json
+import math
+import re
+import uuid
+from io import BytesIO
+from typing import Any, AsyncGenerator, Dict, List, Optional, Tuple, Union
+
+import litellm
+from PIL import Image
+
+from ..decorators import register_agent
+from ..loops.base import AsyncAgentConfig
+from ..types import AgentCapability, AgentResponse, Messages, Tools
+
+SYSTEM_PROMPT = """You are a GUI agent. You are given a task and your action history, with screenshots. You need to perform the next action to complete the task.\n\n## Output Format\nReturn a json object with a reasoning process in  tags, a function name and arguments within  XML tags:\n```\n\n...\n\n\n{"name": "grounding", "arguments": }\n\n```\n represents the following item of the action space:\n## Action Space{"action": "click", "coordinate": [x, y]}\nYour task is to accurately locate a UI element based on the instruction. You should first analyze instruction in  tags and finally output the function in  tags.\n"""
+
+
+def parse_coordinates(raw_string: str) -> tuple[int, int]:
+    matches = re.findall(r'\[(\d+),\s*(\d+)\]', raw_string)
+    if matches:
+        return tuple(map(int, matches[0]))
+    return -1, -1
+
+
+def smart_resize(
+    height: int, width: int, factor: int = 28, min_pixels: int = 3136, max_pixels: int = 8847360
+) -> Tuple[int, int]:
+    """Smart resize function similar to qwen_vl_utils."""
+    # Calculate the total pixels
+    total_pixels = height * width
+
+    # If already within bounds, return original dimensions
+    if min_pixels <= total_pixels <= max_pixels:
+        # Round to nearest factor
+        new_height = (height // factor) * factor
+        new_width = (width // factor) * factor
+        return new_height, new_width
+
+    # Calculate scaling factor
+    if total_pixels > max_pixels:
+        scale = (max_pixels / total_pixels) ** 0.5
+    else:
+        scale = (min_pixels / total_pixels) ** 0.5
+
+    # Apply scaling
+    new_height = int(height * scale)
+    new_width = int(width * scale)
+
+    # Round to nearest factor
+    new_height = (new_height // factor) * factor
+    new_width = (new_width // factor) * factor
+
+    # Ensure minimum size
+    new_height = max(new_height, factor)
+    new_width = max(new_width, factor)
+
+    return new_height, new_width
+
+
+@register_agent(models=r".*UI-Ins.*")
+class UIInsConfig(AsyncAgentConfig):
+    """UI-Ins agent configuration implementing AsyncAgentConfig protocol for click prediction."""
+
+    def __init__(self):
+        self.current_model = None
+        self.last_screenshot_b64 = None
+
+    async def predict_step(
+        self,
+        messages: List[Dict[str, Any]],
+        model: str,
+        tools: Optional[List[Dict[str, Any]]] = None,
+        max_retries: Optional[int] = None,
+        stream: bool = False,
+        computer_handler=None,
+        _on_api_start=None,
+        _on_api_end=None,
+        _on_usage=None,
+        _on_screenshot=None,
+        **kwargs,
+    ) -> Dict[str, Any]:
+        raise NotImplementedError()
+
+    async def predict_click(
+        self, model: str, image_b64: str, instruction: str, **kwargs
+    ) -> Optional[Tuple[float, float]]:
+        """
+        Predict click coordinates using UI-Ins model via litellm.acompletion.
+
+        Args:
+            model: The UI-Ins model name
+            image_b64: Base64 encoded image
+            instruction: Instruction for where to click
+
+        Returns:
+            Tuple of (x, y) coordinates or None if prediction fails
+        """
+        # Decode base64 image
+        image_data = base64.b64decode(image_b64)
+        image = Image.open(BytesIO(image_data))
+        width, height = image.width, image.height
+
+        # Smart resize the image (similar to qwen_vl_utils)
+        resized_height, resized_width = smart_resize(
+            height,
+            width,
+            factor=28,  # Default factor for Qwen models
+            min_pixels=3136,
+            max_pixels=4096 * 2160,
+        )
+        resized_image = image.resize((resized_width, resized_height))
+        scale_x, scale_y = width / resized_width, height / resized_height
+
+        # Convert resized image back to base64
+        buffered = BytesIO()
+        resized_image.save(buffered, format="PNG")
+        resized_image_b64 = base64.b64encode(buffered.getvalue()).decode()
+
+        # Prepare system and user messages
+        system_message = {
+            "role": "system",
+            "content":  [
+            {
+                "type": "text",
+                "text": "You are a helpful assistant."
+            },
+            {
+                "type": "text",
+                "text": SYSTEM_PROMPT
+            }
+            ],
+        }
+
+        user_message = {
+            "role": "user",
+            "content": [
+                {
+                    "type": "image_url",
+                    "image_url": {"url": f"data:image/png;base64,{resized_image_b64}"},
+                },
+                {"type": "text", "text": instruction},
+            ],
+        }
+
+        # Prepare API call kwargs
+        api_kwargs = {
+            "model": model,
+            "messages": [system_message, user_message],
+            "max_tokens": 2056,
+            "temperature": 0.0,
+            **kwargs,
+        }
+
+        # Use liteLLM acompletion
+        response = await litellm.acompletion(**api_kwargs)
+
+        # Extract response text
+        output_text = response.choices[0].message.content  # type: ignore
+
+        # Extract and rescale coordinates
+        pred_x, pred_y = parse_coordinates(output_text)  # type: ignore
+        pred_x *= scale_x
+        pred_y *= scale_y
+
+        return (math.floor(pred_x), math.floor(pred_y))
+
+    def get_capabilities(self) -> List[AgentCapability]:
+        """Return the capabilities supported by this agent."""
+        return ["click"]